Guerneville, California
Population 4,536
This Sonoma County town makes a perfect home base for a wine tasting road trip. You can opt to stay in a traditional property like the Creekside Inn (creeksideinn.com), which offers the wheelchair-accessible Lark Cabin with a roll-in shower; or choose to glamp in style at Russian River AutoCamp, which boasts a custom-built wheelchair-accessible unit. Pick up lunch at the Big Bottom Market (www.bigbottommarket.com) deli, then head out for some wine tasting at Marimar Estate Vineyards & Winery (www.marimarestate.com) — which both offer good wheelchair access. Top off your visit with a stroll through the redwoods at Armstrong Redwoods State Park, which has several wheelchair-accessible trails.