Guerneville, California

Population 4,522
This Sonoma County town makes a perfect home base for a wine tasting road trip. You can opt to stay in a traditional property like the Creekside Inn (creeksideinn.com), which offers the wheelchair-accessible Lark Cabin with a roll-in shower; or choose to glamp in style at Russian River AutoCamp, which boasts a custom-built wheelchair-accessible unit. After you’re settled in,  head out for some wine tasting at Marimar Estate Vineyards & Winery (www.marimarestate.com) which offers good wheelchair access. Top off your visit with a stroll through the redwoods at Armstrong Redwoods State Park, which has several wheelchair-accessible trails.